5 Steps to prevent Heart Disease

Sunday, February 2, 2014

Update on my CIMT scores



            Average CCA Mean               Average CCA Max Region
12-17-09      0.599 mm                               0.741 mm


12-8-11         0.563 mm (.036 less)            0.661 mm (.08 less)


12-20-12       0.566 mm (.003 more)         0.676 mm (.015 more)


12-19-13         0.583 mm (.017 more)       0.709 mm (.033 more)




LDL-P
ApoB
HDL-P
HgbA1C
tg


Weight
1/3/2011



8.8



256.5
3/12/2011
1246
81
37.2
8.2
83


254
5/20/2011
765
81
35.7
7.7
45


257
8/27/2011
1097
63
33.7
10.1
65


246.5
12/6/2011
842

36
9.7
48


256
12/27/2011

62

10



256
5/2/2012

47

8.1



251
7/29/2012
504

28.2
7.4



261
10/12/2012
733

30.9




250
2-23-13
345
53
31.4
8.3
57


256
6-20-13
407

28.2
8.4
64


260
9-9-13
907

26.6
8.2
65


263
11-4-13

50

9.0



257.5
12-20-13
354

26.3
8.4
38


259


I have stayed on my Atkins type diet (low carb, high fat, high protein) for three years. 
My weight stays between 258 and 262 lbs.  

Thus weight loss is not the reason I have such good lipid metrics. 

While my CIMT is getting thicker year, I am still below my high baseline.  

Read more details about this at My quest for normal arteries






3 comments:

  1. Are you concerned about your high A1C?

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    1. Yes I am concerned about my high A1c. I recently went back on basal Insulin but my weight went up to 265 lbs. Last month I stopped my insulin and started Invokana 300 mg. My weight has gone done to 249 pounds. I spent the last week eating in NOLA with alcohol and stayed at the same weight. I reached my maximum weight of 280 pounds after taking insulin five times a day in 2006. For me, I am not a fan of insulin. I would rather stay at Hgb A1c of 8.0 than gain weight. For the arteries I think the weight is worse. I think my metrics show that as long as I keep my LDLp less than 750. I may have microangiopathic risk but I go to the Eye Doc each year and seem okay. I walk a lot a that may help my circulation. I am on ASA 81 mg and 4,000 mg DHA + EPA to help the coagulopathy of Diabetes. My only complication is numbness in my feet. I have A. Fib but don't want to take coumadin. My ultimate treatment for my diabetes is to lose another 20 pounds but if you have read my work about being one of the reduce obese if you realize I have a reduced resting metabolism from the Sponge syndrome and I refuse to go on another sub-starvation low calorie diet. I think Dr. Freedmans approach with the Diet Fix book is good but requires a great deal of discipline to regulate one's life with slow results. I suspect his approach would not help one of the reduced obese lose any weight at 2,000 calories. My exercise metabolism is much reduced from age at 62 yo. There is a 2% reduction of metabolism for each decade. I avoid intense exercise for fear of injury with subsequent total shut down of exercise. Slow and easy increase of intensity may still result in micro-injury setting one up for stress fracture or major tendon injury. This is why I ask people to do a minimum of 20 minutes a day or 8 minutes after each meal with simple easy walking. Best thing is not to be sedentary for more than an hour. Get up and walk the dog. I have been able to avoid gaining weight since Jan 2011 by going on a LCHF diet. To get ketones in my blood I have to be very strict with 20g of carb and exercise. That rarely happens. I believe I don't gain weight because of the natural satiety of high fat high protein diet results in less calories. Being on low carb may help my Hgb A1c but my sugar goes up with large protein meals as well. I have not lost weight on LCHF because I am retired and want to enjoy my life with alcohol and socializing. I think if I stopped wine I would lose weight on my present diet and the new drug has given me a jump on that with the exception of St. Patty's in NOLA last week. Thanks for your question.

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  2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444370/

    High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: Results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS)

    "In this subanalysis of the COSMOS study, we found that baseline HbA1c was significantly associated with change in plaque volume. Notably, no significant regression was observed in patients with high HbA1c at baseline. In contrast, significant plaque regression was observed in subjects with low HbA1c at baseline, even in those with diabetes, although the decreases in LDL-C levels were similar in both groups. This suggests that glycaemic control, in addition to LDL-C-lowering, is an important determinant of plaque progression or regression. "

    "The reduced plaque regression in patients with high HbA1c suggests that hyperglycaemia or diabetes mellitus may be involved in a unique pathogenic mechanism underlying plaque formation in these patients. Indeed, hyperglycaemia could accelerate the development of atherosclerosis through enhanced production of advanced glycation end products, oxidative stress and vascular inflammation, which may contribute to diabetes-specific atherosclerosis"

    "In the present study, there were some marked differences in the changes in lipid levels between the two groups. For example, VLDL-C decreased by 4.1% in the low HbA1c group, but increased by 18.1% in the high HbA1c group. The reason for this difference and its clinical relevance are unclear, because VLDL-C was not associated with plaque progression in univariate analyses, and was not included in the multivariate model. Further studies may be required to understand these results and their possible implications."

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