5 Steps to prevent Heart Disease

Monday, June 1, 2015

HDL's shown to play cardioprotective role



 Link below here:
"This conclusion strengthens the case that at least one of the cardioprotective functions of HDLs is a predictor of cardiovascular events. "



"This study showed an inverse association of cholesterol efflux capacity and HDL particle concentration, but not HDL cholesterol concentration, with incident cardiovascular events."


"Furthermore, because there were few events in the Dallas Heart Study, it was important that the findings were confirmed in an independent cohort, using radiolabelled cholesterol to assess cholesterol efflux capacity.
Such a study is reported in The Lancet Diabetes & Endocrinology, in which radiolabelled cholesterol was used to measure the cholesterol efflux capacity of apoB-depleted serum in a prospective investigation of 1745 patients with incident coronary heart disease and 1749 healthy controls from the EPIC-Norfolk study.10'

Saleheen, D, Scott, R, Javad, S et al. Association of HDL cholesterol efflux capacity with incident CHD events: a prospective case control study. Lancet Diabetes Endocrinol. 2015; (published online May 27.)http://dx.doi.org/10.1016/S2213-8587(15)00126-6.

Also http://m.circ.ahajournals.org/content/130/Suppl_2/A12252.abstract?related-urls=yes&legid=circulationaha%3b130/Suppl_2/A12252

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