5 Steps to prevent Heart Disease

Sunday, June 28, 2015

Weight loss with diet and medicine not yet shown to improved mortality? Bariatric surgery has.

I am studying the Handbook of Obesity for my Obesity Boards in Dec 2015.  It is edited by Bray and Bouchard.


In Vol. 2 Fourth edition p385-386 are the following excerpts:


“However with the the exception for the Swedish Obese Subjects (SOS) trial, controlled interventional studies demonstrating that weight loss is in fact reducing mortality have been lacking”

“To date most observational epidemiological studies have indicated that overall and cardiovascular mortality is increased after weight loss even in subjects who were overweight or obese at baseline.”

“...the observed weight loss might be the consequence of conditions that lead to death rather than the cause of death.”

“Lifestyle interventions to protect against diabetes have not prevented cardiovascular events after 10-20 years of follow up.”


References:
24-Yaari. Voluntary Wt. loss. Am J Epidemiol 1998: 148: 546-555


25- Wannamethee. Older men who lose weight. Am J Epidemiol 2000; 151:667-75


26- Li G. Long term-effect of life-style interventions. Lancet 2008;371: 1783-9


27- Uusitupa. Morbidity in Finnish Diabetes Prevention Study. PLoS One 2009; 4e5656

28- Nissen SE. Rimonabant in STRADIVARIUS TRIAL. JAMA 2008; 299 1547-60

No comments:

Post a Comment