The Lean maintain their weight
because
their brain
listens to
their small intestine.
slide from Jeffrey Sicat OMA lecture
This is where the new diet medicines help the reduced obese maintain their weight loss and help the obese lose weight.
"The action of insulin on the
REWARD PATHWAY DOPAMINERIC neurons is thought to additionally contribute to development of obesity, since signaling of these higher neuronal circuits can override hypothalamic signaling.
Wang et al. have proposed that reward-driven overconsumption of high-fat, high sugar and energy dense foods leads to neuronal insulin resistance, dysregulation of dopamine homeostasis, and hypodopaminergic reward deficiency syndrome. "
Quoted paragraph from page 7 of
The Clinican's Guide to the Treatment of Obesity
Adrienne Youdim Editor
because
their brain
listens to
their small intestine.
This is where the new diet medicines help the reduced obese maintain their weight loss and help the obese lose weight.
"The action of insulin on the
REWARD PATHWAY DOPAMINERIC neurons is thought to additionally contribute to development of obesity, since signaling of these higher neuronal circuits can override hypothalamic signaling.
Wang et al. have proposed that reward-driven overconsumption of high-fat, high sugar and energy dense foods leads to neuronal insulin resistance, dysregulation of dopamine homeostasis, and hypodopaminergic reward deficiency syndrome. "
Quoted paragraph from page 7 of
The Clinican's Guide to the Treatment of Obesity
Adrienne Youdim Editor
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