5 Steps to prevent Heart Disease

Thursday, June 30, 2016

Best drug to get off Insulin?

The two times I have gone on Insulin I have gained weight.
I remember in times past I was told Insulin does not cause weight gain by Endocrinologists.
While studying for my ABOM exam, Insulin was high on the list of drugs known to cause weight gain.

On 3-4-14 my Invokana(canagliflozin) switch  experience was very successful for me.

 I lost about 20 pounds during it while not changing my Atkins diet or increasing from my usual 20-40 minute walk a day. I went off Insulin.

Experts Agree Jardiance Reduces Cardiac Deaths  was in the news today:

"Late yesterday, expert advisors to the FDA voted by a margin of 12-11 that the diabetes drug Jardiance (emagliflozin) does indeed cut the risk of cardiovascular deaths for patients with type 2 diabetes who have a history of cardiovascular disease. The committee was unanimous in its agreement that the drug offers good cardiovascular safety. But the vote was much closer on the question of whether it clearly protects against cardiovascular deaths."

My endocrinologist put me on Invokana rather than the newer Jardiance   because it had already been used in Europe.  

"On July 4, 2011, the European Medicines Agency approved a paediatric investigation plan and granted both a deferral and a waiver for canagliflozin (EMEA-001030-PIP01-10) in accordance with EC Regulation No.1901/2006 of the European Parliament and of the Council.[15]
Canagliflozin was approved by the FDA on March 29, 2013, and became the first SGLT2 inhibitor in the United States.[16][17]

Dr. Sarah Halberg TED talk 18 minutes
Reversing Type 2 Diabetes Starts with Ignoring the Guidelines

Metformin and Victoza are two diabetic drugs that drug companies will pay for which also help obesity patients.

I started Qsymia on June 24, 2015:  241 lbs 152 glucose 0.8 glucose

  I have been able to taper off Actos without worsening Hgb A1c as I was losing another 20 pounds during the tapering period.

Actos taper

Actos 40 mg to  30 mg            9-6-15   236 lbs  117 glucose ketones 2.5
                          22.5 mg       9-21-15   237 lbs   139 glucose ketones 1.5
 Stopped Actos                     11-7-15    228 lbs   131 glucose ketones 1.6 

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