Poor evidence for TG/HDL ratio as supreme marker for ASHD

Ivor Cummings book Eat Rich Live Strong says that Triglyceride/HDLc ratio "reigns supreme" over and is vastly more predictive than the LDL value 

                                      Reference one: 340 cases

Reference two: 544 women

Reference  three: 220 males 154 females

Ivor has used only 1258 people in his evidence. 

 In Cholesterol Treatment Trialists’ (CTT) Collaboration1

Lancet. 2010 Nov 13;376(9753):1670-81. doi: 10.1016/S0140-6736(10)61350-5. Epub 2010 Nov 8.

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomized trials.

INTERPRETATION:

Further reductions in LDL cholesterol safely produce definite further reductions in the incidence of heart attack, of revascularisation, and of ischaemic stroke, with each 1·0 mmol/L reduction reducing the annual rate of these major vascular events by just over a fifth. 

There was no evidence of any threshold within the cholesterol range studied, suggesting that reduction of LDL cholesterol by 2-3 mmol/L would reduce risk by about 40-50%.

FUNDING:

UK Medical Research Council, British Heart Foundation, European Community Biomed Programme, Australian National Health and Medical Research Council, and National Heart Foundation.

6 of the trials:

1-  Search Trial 2010

2- IDEAL TRIAL 2005

3- TNT trial 2005

4- A to Z trial 2004

5-- PROVE-IT Trial 2004

6- SSSS trial 1994 Statin vs. Control "Simvastatin produced highly significant reductions in the risk of death and morbidity in patients with CHD followed for a median of 5-4 years, relative to patients receiving standard care."