Good charts on genetic studies and drug studies

APOC3, Coronary Disease, and Complexities of Mendelian Randomization link

Below is RED CIRCLE mentioned on twitter
Two new studies report that triglyceride (TG)-lowering mutations in APOC3 reduce coronary heart disease (CHD) 

 The red circle represents the CHD reduction (~46%) that is predicted for a loss-of-function mutation in APOC3 (R19X) (Crosby et al., 2014; Pollin et al., 2008).