5 Steps to prevent Heart Disease

Sunday, April 21, 2019

nostrum for Alzheimer's

Joe,                                                                          10/10/2018
  Sustained release berberine  has an incredible number of uses because it controls carbohydrate and fat metabolism. 
 It help in weight loss. 
It prevents cardiac and liver damage and damage to the kidneys.
 It is incredibly useful for the treatment of type 2 diabetes because it helps control blood sugar (glucose). 
I and a few of my friends have really been amazed at its all-around effects. 
 It has been shown to help with drug resistance in cancer and higher doses actually kill cancer cells.
 Biochemically these statements seem impossible but it has central control of metabolism –AMP kinase stimulation. 
It has now been shown to prevent vision degeneration-so called wet AMD. 
Most of the what this herbal product does is to control oxidative and nitrosative stresses which control most chronic diseases. 
By using the other sustained released products that you and your company make –the death rate from chronic diseases will take a massive plunge. 
This will be a revolution in the prevention of diseases –instead of the treatment of diseases that wind up causing the demise of humans.
Best Regards,

From: Vandyke, Knox <kvandyke@hsc.wvu.edu>
Sent: Tuesday, October 09, 2018 1:20 PM
To: Joe Brunner <joe@endur.com>
Subject: RE: Alzheimer

Joe,                             10/9/2018
  I’m not sure if you received my recent message so I will resend it.
I’m not sure APO-E assay is linked to Alzheimer’s disease. The literature is not clear. Besides you have to do a spinal tap which causes problems.
I tried to get Ter interested in making sustained release berberine HCl. 
This is a fantastic supplement –because it controls blood glucose in type 2 diabetes and probably type 1 as well. 
It prevents heart damage by inhibiting cardiac fibrosis. 
It prevents damage to the eye by stimulating eye receptors. 
It has been found to inhibit drug resistance in cancer.
 It has no side effects.  it creates weight loss by decreasing hunger.
Ter said it is very yellow and would contaminate the work area.
 But, if you could isolate one press with a plastic hood—I would think it could be well controlled.
 It is quite inexpensive and the sustained release form would sell very well.
Best Regards,

Nothing like puberty to help a diet

Age 15 above 
I used an adult BMI chart.

See the rest of my photos in the book: 
The Chronic Disease of Obesity. link

Thursday, April 18, 2019

Get a hearing test early. It may suggest you are at risk for Dementia

I might be interested in the last book but it might be too depressing for me

The other six books are nonsense.  It sells the false hope of Alzheimer’s.

My book is more optimistic in the short run.

Don't waste your time looking for a cure.

Use your last years to have fun.

16 months after my Dx was made I am optimistic.

My wife and I made  two more vacation plans for 2020.

I truly believe I will finish year two of my  series.

I am already writing about the fifth month of the second year.

When I first had the Dx confirmed in Dec 2017, I looked up the data on Aricept.

Aricept seemed to prevent decline of cognition for two years. Thus I only expected two
good years

If you survive 5 years after a diagnosis of cancer you are considered a survivor.

This is why I suggest people don't read book about the end stage of the disease.

Too much doom and gloom.

Instead get a hearing test. If you have hearing loss do an aggressive testing for dementia to catch it early.

Tuesday, April 16, 2019

Update on my 11 year weight loss maintenance

I returned from Houston OMA conference on April 8, 2019

I went to an Obesity conference in Houston, the first weekend of April, 2019.  I came back and my weight went up to 217.

When I want to get back down I have this restrictive diet but no hunger.  1800 calories.

I am 215 pounds and the BIA scale says my basal metabolic rate is 1765 calories.
This calculation does not take into account that I am REDUCED OBESE with a reduced resting metabolic rate.  I feel cold all the time.
I am on Invokana so I lose 200 calories of glucose each day in urine.

Problem is this calculation does not take into account that I am a REDUCED OBESE with possibly 38% reduction in exercise metabolism.  I try to walk 5,600 steps (3 miles) a day.  For a lean person they burn 300 calories with walking. For me I burn only 186 calories a day.

As Yoni Freedhoff MD, Eric Westman MD and Columbia University sports Specialist taught me is that;


I try to walk at least 5,000 steps a day to not be classified as sedentary.
10,000 is a good goal but difficult to reach each day. That would be I hour of walking for me.
Evidence shows that Alzheimer's patients need to exercise 150 minutes a week.
I walk 140 minutes a day but I go up and down the stairs quite a bit.

The Fitbit says my average calorie burn is 2,942.

For the reduced obese this is not true, as we have reduced exercise metabolism.

My BIA scale says for moderate exercise I burn 2654 calories.
For light exercise I burn 2471 calories.

Let's use the lowest number 2471.
Then lets add the 200 calories I lose from Invokana.

Thus I can eat 2,671 calories a day and maintain my weight.

On the Bon Vivant diet I often eat at least 2500 calories.
Ancel Keys starvation diet vs The Bon Vivant diet

On lower calories I have been down to 200 lbs.

That is where I want to be but I easily pop back up to 210 pounds.

I take solace that the quotes from Yoni's book The Diet Fix that concur with my book The Chronic Disease of Obesity

As Dr. Mike Rosenbaum said at the OMA conference.
There is a great deal of evidence that the set point plateau goes up and the body always tries to get back there with weight regain due to low leptin.

NO EVIDENCE that the set point can be lowered again.

Even at 215 pounds my body continues to get me back to 280 pounds with low metabolism and hunger.
I believe I handle my hunger with Belviq, Victoza, Metformin, and Caffeine.
Nothing I can do to speed up my resting or exercise metabolism.

Slide from Houston OMA meeting 2019 and Dr. Mike Rosenbaum.

Please compare water pounds and total lean pounds with the changes in weight changes.
Shows that weight doesn't tell you everything

More false hope claims not substantiated for Alzheimer’s

More false hope claims not substantiated.

This is why I write in my book to not chase these nostrums but to have a drink and socialize. Have fun.  

Dr. Bredesen’s Protocol critique

I memorized 15 items in my Memory Palace.

I was diagnosed with Alzheimer's in December 2017, 16 months ago.

I was delighted to find that I could remember 15 items via my Memory Palace.

Last year on my last memory test I forgot the fourth item on a list of four things they asked me to remember.  I tried to use color association back then and it failed.  Stress of the test?

In the book they suggest you make 12 memory palaces.
The author says it takes about an hours work to remember 10 minutes of a poem

I would like to remember two songs.

A Red, Red Rose

O my Luve is like a red, red rose 
   That’s newly sprung in June; 
O my Luve is like the melody 
   That’s sweetly played in tune. 

So fair art thou, my bonnie lass, 
   So deep in luve am I; 
And I will luve thee still, my dear, 
   Till a’ the seas gang dry. 

Till a’ the seas gang dry, my dear, 
   And the rocks melt wi’ the sun; 
I will love thee still, my dear, 
   While the sands o’ life shall run. 

And fare thee weel, my only luve! 
   And fare thee weel awhile! 
And I will come again, my luve, 
   Though it were ten thousand mile.

I have memorized it before and I sang it to my wife on cruises. 
But I forget and I have to refresh. 
 I would really like to have it at any time.  

My Dad was in the Air Force for 20 years. 
In my childhood grew up on Air Force bases. 
I was very proud of my Dad being a Captain.
I knew a few verses of the Air Force Anthem.

Lyrics to the Air Force Song 

Off we go into the wild blue yonder,
Climbing high into the sun;
Here they come zooming to meet our thunder, 
At 'em, boys, Give 'er the gun! (Give 'er the gun now!) 
Down we dive, spouting our flame from under,
Off with one helluva roar! 
We live in fame or go down in flame. Hey! 
Nothing will stop the U.S. Air Force!
Minds of men fashioned a crate of thunder, 
Sent it high into the blue;
Hands of men blasted the world asunder;
How they lived God only knew! (God only knew then!)
Souls of men dreaming of skies to conquer 
Gave us wings, ever to soar! 
With scouts before And bombers galore. Hey! 
Nothing'll stop the U.S. Air Force!
I suspect each song will take an hour to put into two memory palaces. 

Monday, April 15, 2019

Comment's on GINA KOLATA'S NYT article on Alzheimer's

My review of article at this link

I have a very different view of Alzheimer's.

Please read my book on YEAR ONE of having Alzheimer's

Get diagnosed early so can enjoy the years left to you.

The gloom and doom is late stage disease.

I am waiting for when I forget I have Alzheimer's. YEAR ONE link above

This is a different type of book on Alzheimer’s.
There are no claims on how to prevent this dementia. 
There are no claims on how to cure Alzheimer’s.
In a cancer diagnosis, the patient can fight and win. 
In Alzheimer’s, no one has fought and won. 
Don’t fight, have fun.