Treatment of Prediabetes.

Treatment of Pre-diabetes 2015 link 

Conclusion:

In conclusion, we recommend strict lifestyle modification for patients with IGT ± IFG.

Another option is to initiate pharmacotherapy with metformin plus low-dose pioglitazone.

In high risk IGT individuals long-acting GLP-1 analogue {Victoza (liraglutide) or Byetta (exenatide)} use as well as diet plus exercise may be another option.

Each component of this approach is effective in type 2 DM prevention and turning IGT back to normal.

Depending on evidence described earlier, we believe “combination therapy” would especially be preventive for microvascular complications and is associated with lower adverse effects. Also, pharmacotherapy with generic drugs may be cost effective.

This is what I proposed in my book The Chronic Disease of Obesity Feb 2018 as well as add a diet medication such as belviq, contrave or qsymia.