Even serious weight loss doesn't reduce your overall number of fat-holding cells. link 2008
by Michael Hopkin
"The number of fat cells in your body remains constant throughout your adult life, a new study has found."
"Children, on the other hand, may put on extra fat by increasing the overall number of these cells in the body."
"Adults who gain or lose weight may do so through changes in the size of the fat cells, also called adipocytes, that constitute fatty deposits in the body."
"Although the number of fat cells remains constant in adulthood, Spalding and her team found that it is not the same cells persisting for ever. There is a dynamic process of cell death and replenishment."
"The researchers also measured 20 people who were obese and had 'stomach stapling' surgery to reduce food intake. When Spalding and her team measured these volunteers again two years after the procedure, they found no reduction in fat-cell number: the subjects still had over 80 billion individual fat cells in their bodies, Spalding and her colleagues calculate. This despite losing an average of 18% of their body weight. It was the volume of each individual fat cell that was reduced, rather than the number, they report in Nature1."
"If cell biologists can work out exactly how this cell replenishment is regulated, it might be possible to design drugs to interfere with this process — potentially helping people to keep weight off once they have lost it."
by Michael Hopkin
"The number of fat cells in your body remains constant throughout your adult life, a new study has found."
"Children, on the other hand, may put on extra fat by increasing the overall number of these cells in the body."
"Adults who gain or lose weight may do so through changes in the size of the fat cells, also called adipocytes, that constitute fatty deposits in the body."
"Although the number of fat cells remains constant in adulthood, Spalding and her team found that it is not the same cells persisting for ever. There is a dynamic process of cell death and replenishment."
"The researchers also measured 20 people who were obese and had 'stomach stapling' surgery to reduce food intake. When Spalding and her team measured these volunteers again two years after the procedure, they found no reduction in fat-cell number: the subjects still had over 80 billion individual fat cells in their bodies, Spalding and her colleagues calculate. This despite losing an average of 18% of their body weight. It was the volume of each individual fat cell that was reduced, rather than the number, they report in Nature1."
"If cell biologists can work out exactly how this cell replenishment is regulated, it might be possible to design drugs to interfere with this process — potentially helping people to keep weight off once they have lost it."
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