I have Stephan J. Guyenet's book, The Hungry Brain.
I missed his references to the central action of Insulin on the brain.
In his tweet below he writes, "The effect of insulin seems to be smaller and less consistent though."
I guess he is comparing it to low levels of leptin action on the brain?
My article on the paradoxical effects of insulin link
Excerpts:
1-Although many factors affect fat cells, the hormone insulin exerts dominant anabolic control. (peripherally)
2- Catabolic state of uncontrolled diabetes despite elevated blood glucose
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