Tuesday, September 29, 2020

This is a special night for me

 My Alzheimer's was diagnosed in Dec. 2017


I was very uncertain at that time if I would be able to vote or even understand what was going on with the 2020 election.

To my delight, I received my Florida mail-in ballot.

Very exciting as I have been eagerly anticipating getting the ballot.

Making the occasion even more special is that the Biden Trump debate begins in one hour 12 minutes. 

I have already filled out my ballot. 






Friday, September 25, 2020

 Chasing rainbows in the pursuit of happiness

Let's hope it works. 

I have an appointment with a naturalist who does the Recode protocol.

It's the cognoscopy blood work that I am most interested in.

The first visit is with the Doctor that founded the group. 

I guess he gives up the pitch so we don't faint at the price. 


Fighting Alzheimer's with Fortitude. 

 Title of the sixth book




Tuesday, September 22, 2020

GOP be careful for what you wish for.

 GOP be careful about what you wish for. 


I was a Republican until they became the 

anti-science party. 

I support free choice for women on abortion.

However, I am okay with President Trump's choice. 


 

I'm also okay with SCOTUS repealing Roe vs Wade. 

Technology has made abortion unnecessary if proper care is taken.  

There are pills to take if unprotected the day after.  

I say let the GOP get what they want. 

I think it is like the dog that catches the car. 

What will they do now?

I don't endorse this I just think we don't need to fight this emotional battle anymore.

Sometimes losing is winning

I think a conservative court overall is a good thing. 

A good balance to when the Dems have the majority in Senate and House and the Presidency. 

If a solid block of GOP conservatives overturns many progressive issues it will call for stuffing the court with three more justices by DEMS. 

 I don't think there is a solid far-right SCOTUS COURT. 

I think confirming Justice Barret before Nov 3

 will happen.

Ultimately I think GOP will be sorry they got what they wished for. 











Tuesday, September 15, 2020

Homage to COVID19

 Homage to Covid19 

No haircut since Jan 2020

I am thinking of taking another photo like this in December to put on the back of my next book

The Pursuit of Happiness by an Alzheimer's patient. Year 3






Below is my updated photo was taken on December 9, 2020.  Planning to put it on the back of my next book: The Pursuit of Happiness with Alzheimer's YEAR THREE.  Hopefully to be published in Feb 2021 






Photo from 1970 while in London for the summer working on Oxford street at Woolworths





The New Hair Style during Covid19 epidemic










It doesn't take high dose statin to get great lipid numbers.

 I only take:

1- Lipitor 10 mg/d

2- Enduracin 1,000 mg/d

3- Lovaza 4,000 mg/d

On Low Carb High Fat diet 60% fat

I have DM2


1-Lab June 2020






2- Lab Sept 10, 2020

Total Cholesterol  115

minus HDL.          74

                              41

minus LDLc          31

 Remnants             10


3- Quest lab Feb 2020 link



Friday, September 11, 2020

I feel that my Alzheimers is worse.

 This week I screwed up writing a check to my wife. 

I filled it out to my last name rather than than her last name.  

It looked worked but I thought it was okay.

The check was for $125 but I wrote One hundred twenty dollars. 

Our bank let her have $120.


When I go to sleep I have routine 

where I take two deep breaths and then I say

Peace

Serenity

Tranquility

Contentment


Two nights ago I couldn't remember the T word. 

I made a memory bridge.

I would think of a train carrying Quails. 

I remember the memory cue but could not remember the word till I woke up this morning. 

It was disturbing to me during the night half asleep trying to remember the word Tranquility. 


I wonder if my Alzheimers is getting worse. 

It may be due to my higher Hgb A1c.

I recently began some ice cream and bagels. 

My ketone level fell below 1.0 and my glucose levels went up.

It may be due to my low testosterone after stopping injections. 


I started testosterone 100 mg/ week today.

I am going to get another skin glucose monitor again.  Previously it helped me stay on my fasting.

I will use it again when I am tempted to eat a carb during the day.

Today after one cup of ice cream last night:

Glucose 171 (I had been running glucose 220)

Ketones 1.4

Weight 208.8 

I have followed the advice from The End of Alzheimers by Dr Dale Bredesen with the following.

Revisiting testosterone link

When I increased my testosterone link

What I do on Bredensen's ReCODE link


I am a physician and can do these complicated maneuvers. 

For the average family they might have to be followed by their physician each month. 

However Alzheimers is inexorable.  

We can't really know if these items make any difference.  

From The End of Alzheimers :


Perhaps I am not getting worse. 

In Jan. I had a bad day:



If I am stressed or perhaps overworked I may not perform as well, as simple as that.

Nothing to do with my Hgb A1c or Testosterone.  

However, no down side on trying to get better glucose results
 and improve libido with testosterone.

I will also be resuming Cialis this week.
















Thursday, September 10, 2020

Surprising advice from my new Endocrinologist

 Previously I wrote about being fired by my former Endocrinologist link


Today my new Endocrinologist gave me some surprising advice 

Here are my last Hgb A1c results



I told him how my excellent result fo 6.7 was when I initially did Intermittent fasting.

However the next result on 14-16 hour fasting was not as good at 7.2

Then I found my fasting glucoses going up with IF 


Thus I stopped intermittent fasting and my A1c went up 8.6

I went over all this with my endocrinologist.
 
He surprised me by saying he was not going to get after me about this.  

He said I was older and it was alright to enjoy my life.

He knows I have Alzheimers.

















Sunday, September 6, 2020

My review of The End of Alzheimer's Program by Dr Dale Bredensen

 My review of The End of Alzheimer's Program by Dr. Dale Bredensen.

The First Protocol To Enhance Cognition and Reverse Decline At Any Age.


I read Dr. Bredensen's first book, The End of Alzheimer's. Here is my review:

The second book has improved my opinion of his theory. 

New opinion of Bredesen link

I am less pessimistic about the course of my Alzheimer's since I have completed nine months of my YEAR THREE book.

Thus I feel more charitable towards Dr Bredesen's books.

I was very upset with the title The End of Alzheimer's. 

His Avery publisher probably wrote the title of the book.

I was most impressed by my finding of his data the Julie Gregory may be the first survivor of Alzheimers.


The second book was published in 2020 and is dedicated to her (Julie G).

Part II of the book is co-authored by her.  

8 years of reversal of Alzheimers by Julie Gregory that is well documented

 according to published articles. 

A year ago I would have argued she was impaired by anxiety not Alzheimers. 

 Certainly only an obsessive compulsive person could maintain such adherence to the many facets of the ReCode program.

Presently, I am more willing to accept her case as it is presents itself now, 

since I myself have done better on my tests in the 8th month of my third year since my diagnosis since December 2017.

My MOCA score improved link

The program book is very good at explaining details of how to achieve the goals of improvement of cognition. 

For these reasons, I have increased my rating to 3 stars.  

His diet is impossible for the average person compared to Atkins.  









Friday, September 4, 2020

Don't want to give up my bacon and alcohol.

 Page 88 The End of Alzheimers Program 2020





Dr Bredesen writes individuals need to find the plan that works for me. 
I have maintained 70 pound weight loss since 2011 when I began an Atkins type diet as shown in the third pyramid below.
I eat 60% fat.
Most of it saturated fat.
I have Diabetes type 2. 
I have been able to stay off insulin. 
The bacon and alcohol satiate me and allow me to avoid sweets. 
If I were on Julie Gregory's diet I might not live longer 
it would just seem to me as if I did. 



Dr Dale Bredesen does not like the original food pyramid. 
Neither do I.







Dr Dale Bredesen pyramid for cognitive improvement





Low Carb High Fat Diet Pyramid that I follow



Why haven't my MOCA scores gotten worse?

 This summer I seem to have done better on my annual visit to KUMCR and Memory center.

I thought it might be that testing has become much less stressful for me. 

However after reading Dr. Dale Bredesen's new book The End of Alzheimer's Program that he may have found the first Alzheimers survivor by the name of Julie Gregory.

p62 "since Julie who is apoE4/4 positive (homozygous), has reversed her own cognitive decline"

from the second book Program.  


From the first book The End of Alzheimers published 2017 on page 219 Julie writes extensively on her routine using the ReCODE method, 

"At age 49 she became lost in familiar places, failing to recognize faces, and losing her memory." 

p 220

"her cognitive evaluation showed her to be at only the 35th percentile for her age when she started treatment.  However after several months on the program, she noted marked improvement,  and her cognitive evaluation rose to the 90th percentile. It remans that 5 years later (and counting)."

This was written in the 2017 edition.

The second book was published in 2020 and is dedicated to her (Julie G).

Part II of the book is co-authored by her.  

8 years of reversal of Alzheimers by Julie Gregory that is well documented

 according to published articles. 

A year ago I would have argued she was impaired by anxiety not Alzheimers. 

 Certainly only an obsessive compulsive person could maintain such adherence to the many facets of the ReCode program.

Presently, I am more willing to accept her case as it is presents itself now, 

since I myself have done better on my tests in the 8th month of my third year since my diagnosis since December 2017.

I believed I maintained my status with Namzaric for the first two years. 

This third year I was on Intermittent fasting for 14 hours a day for 8 months with increases in my ketone levels.  Normally I have always been in ketosis greater than 1.0 since 2011 when I started Low Carbohydrate High Fat diet.

With Intermittent Fasting I would reach much higher levels of ketosis.

 Perhaps this is the key to my improvement, which is a major component of THE PROGRAM.


There is another possibility.

For one month I took Cialis every other day.  My testosterone level also was very high and I had a very strong libido.  

My Ten Step Program link

My vitamin D level went up to 88 with bolus doses of 10,000 units each weekend times 4 on top of a lower daily dose.

Vitamin D link


On the negative side I did have a concussion. 

Post Concussion Syndrome link

I also increased the amount of Zinc I was taking in addition to the multivitamin pill I took each day.

By June 15, 2020 I began having more Hope about my prognosis with Alzheimers as I was 30 months into my diagnosis and I had not expected to do so well.  

Hope but not False Hope. link









Thursday, September 3, 2020

I am gaining more respect for Dr Dale Bredesen

 I am gaining more respect for Dr. Dale Bredesen and his books. 

My first Amazon review was in April 2019.

I was brutal. 

One star. 


Later in October 2019 I still gave him only one star
 but with more explanation




Subsequent to this review I made several more in my  Blogs.  

What I agree with Dr Dale Bredesen on. link

I actually do much of what Dale Bredesen MD advises. 


1-I keep my LDLp below 1,000.  (LDLp is the particle count which is more accurate than LDLc)

2-I keep my systolic blood pressure under 120.

3-I also exercise 150 minutes a week

4-I have  a sleep apnea machine since 2004 and sleep 7-8 hours a day

5- He advises Magnesium threonate 2 gram a day.  I take 3,750 mg of Magnesium maleate a day which has helped my leg cramps at night tremendously.

6- I get my Resveratrol with wine

7- I get Nicotinamide riboside 100 mg in Enduracin (nicotinic acid)  2,000 mg which I take for cholesterol, triglycerides and HDLc. Both chemical are in the same molecular pathway.



8- He advises Omega 3: DHA 1g EPA 0.5 to 1.0 gram 
I take 4,000 mg of Lovaza which breaks out as:
DHA 375 x 4= 1500 mg
EPA 465 x 4 = 1860 mg

Update March 8, 2021.
Now I take 3 of these tablets a day.
DHA 375 X3 = 1125
EPA 465 X3 = 1395

I reduced those omega piils and then started taking Antarctic Krill oil 
Krill oil has 
 EPA 80mg
DHA 52 mg
I end up now with less EPA and DHA.  
I did it to get the carrier of DHA  to go past the brain barrier into the brian. 
DHA is not made iin the.  No way to know if my good DHA level in the blood gets past the blood brain barrier.  
It will be interesting experiment of one person. 

I made this decision based on Dr Michael Davidson's information below. 






9- I take Vitamin D 2,000 to 4,000 IU a day


9- I take Vitamin D 2,000 to 4,000 IU a day

10- I take Citalopam for depression or rather dysphoria. 

11- I take Testosterone 100 mg IM

That leaves 20 things I don't do on Bredesen's list

The other 21 items are nostrums that have no human trial evidence. 

I am now reading the second book in the series:

The End of Alzheimer's Program 

The first protocol to 

Enhance Cognition and Reverse Decline 

At any age.


I am less pessimistic about the course of my Alzheimer's since I have completed nine months of my YEAR THREE book.

Click below for

Free view of my new AZ book


Thus I feel more charitable towards Dr Bredesen's books.

I was very upset with the title The End of Alzheimer's. 

His Avery publisher probably wrote the title of the book.

I will start my review of his book briefly now.

I have done better on my MOCA test scoring 30/30

MOCA test link


Thus from my personal experience I am not so skeptical of Dr Dale's list of "survivors". I don't like the use of that term as people with AZ can live as long as 20 years.


I find my switch to Bigalow green tea is endorsed in the book. 

I will go back to only eating 72% coco chocolate.

I will still drink my  glass of whole milk each day

I was on 14 hour fast each day on LCHF 8 months. 

Months of ketone level on IF link

Last 2 weeks of IF my glucose went up link

Anxiety from stress of fasting link



It may well be that the 8 month Intermittent fasting with high ketones levels did improve my cognitive ability. 

However I also started a Cialis/testosterone plan for a month till the my testosterone was too high.

I have stopped the Cialis, Testosterone and Intermittent fasting.  

I got lab work to see if I can resume testosterone.  I have n0 libido

Alcohol



I have tolerated my alcohol for the last 3 years. 

My See No Evil bar link


I have been having bagels in the morning and some ice cream at night, as comfort food in this time of Covid 19 shut down.

Subsequently my morning ketones run around 0.5.  

Thus I will experiment with exogenous ketones as Dr Bredesen advises. 










Wednesday, September 2, 2020

Disturbing Dream

 


At the beginning of I am waiting for when I forget I have Alzheimer's, I wrote about an uplifting dream I had.

Last night I had a disturbing dream which I think was a metaphor for my future with Alzheimers.


I arrive at this place with luggage.

I enter through a gate and pass though a large yard.

Later when it was time to leave the dogs had been left out. 

They were large hairy dogs probably similar to my Newfoundland but more amorphous.  

We have 3 Newfoundlands in the family but if I had recognized them I would have called out their names.

 When I left the building and closed the door they impeded my progress to leave.  They didn't bite or hurt me, they just overwhelmed me physically slowing my progress to the gate.  At times I was crawling through them.

Finally outside the gate I realize I forgot my luggage and I have to go back through the dogs. 

 Inside the building the staff tell me they don't have my luggage. 

Nonplussed(meaning I was surprised and confused so much that I was unsure how to react).,  I set out to get through the dogs to the street. 

When I woke up, I told the dream to my wife.  

I tried to piece the fragments of the dream together which was difficult but the emotional content was unmistakable,  I was disturbed about the experience. 

I interpreted the dream as a metaphor for my future as an Alzheimer's patient. 

Life will be a struggle just to accomplish simple things. 

Dealing with people will get more difficult in tedious ways that make communication impossible.

I won't understand what is happening.

And the subsequent feeling will not be pleasant. 





update trials of Alzheimers

 The best part of the day is when I have a bowel movement.   Recently started Miralax. I found MOM too harsh. Pacing helps but I get exhaust...