This is my analysis of the last 10 items of Dr. Bredesen
TWENTY ONE
BIOIDENTICAL HTT
Specifically for:
Thyroid
Adrenal
Sex hormones
I have been taking Testosterone IM for many years since 2011.
My level was low.
TSH is always checked and treated in my practice and general guidelines.
Hypothroidism can cause myxedema coma and madness and is treatable with thyroid medicine.
I have never seen this diagnosis in my 48 year career.
I use to give estrogen replacement for menopause. Years ago I stopped when it seemed to cause problems.
I would consult an endocrinologist or your GYN doc for their recommendation.
Addison's disease is also a rare disease.
Treatment does restore health.
I think it is up to your MD to decide whether to do the tests to make the diagnosis.
TWENTY TWO
SPM
Specialized pro-resolving mediators
If hsCRP greater than one.
Not clear to me why 4 grams of Lovaza is not sufficient?
TWENTY THREE
Methylcobalamin 1mg and methylfolate 0.8-5 mg
PSP 20-50 If homocysteine greater than 6
if B12 less than 500
I think all suspected dementia patients should get B12 levels as per guidelines
In past I did homocysteine levels on all my elderly patient I got away from due to lack of results or the current guidelines at the time.
I have no problem with patients checking their homocysteine.
TWENTY FOUR
ALPHA-LIPOIC ACID 100 MG
N-acetylsteine 500mg
cinnamon one quarter teaspoon
berberine 300-500 mg 3x a time
or
metformin
If fasting insulin greater than 4.5
or fasting glucose greater than 90
or Hemoglobin A1c greater than 5.5
I like Dr. BREDESEN's the criteria above which can be a diagnosis of pre-diabetes which present guidelines do not yet address yet.
I agree with Metformin for a pre-diabetic.
These are tests you should have done.
The four medicines listed before metformin I would not advise.
TWENTY FIVE
ZINC PICOLINATE
ALHA-LIPOIC
N-acetycysteine
PSP
Mn
Vitamin C
IF ZINC LESS THAN 80
or
COPPER/ZINC LESS THAN 1.3
I never did a Zinc level. Seems absurd with American diet.
TWENTY SIX
SAM-E
OR
FOLATE
IF THERE IS DEPRESSION
This may be the most ridiculous recommendation and probably would be grounds for losing his license if the patient committed suicide.
I have treated depression with multiple drugs since 1980 especially PROZAC
TWENTY SEVEN
Huperzine
Take if after 3 months on ReCODE and memory is the primary problem and not on Aricept.
TWENTY EIGHT
CIRS evaluation
Cholestyramine
Intanasal VIP
If evaluation indicates type 3
high C4A
high TGB-beta 1
low MSH
This is incredible.
I would not do this.
TWENTY NINE
Detoxification
xification protocol.
If metals or biotoxins idebtified
This had nothing to do with Alzheimers.
Thirty
Specific antibiotics or antivirals
If infections identified
As an infectious disease specialist I was called to consult of fever of unknown origin.
Alzheimer's is not in the differential of FUO.
Fever and infection can make anyone delirious.
Should not be on an Alzheimers list or long term memory loss.
Thirty one
Discontinue or minimize medications that interfere with cognitive function
This is always a good practice in medicine.
I have done this many times with good results.
However this is not Alzheimers.
It is medication induced.
TWENTY ONE
BIOIDENTICAL HTT
Specifically for:
Thyroid
Adrenal
Sex hormones
I have been taking Testosterone IM for many years since 2011.
My level was low.
TSH is always checked and treated in my practice and general guidelines.
Hypothroidism can cause myxedema coma and madness and is treatable with thyroid medicine.
I have never seen this diagnosis in my 48 year career.
I use to give estrogen replacement for menopause. Years ago I stopped when it seemed to cause problems.
I would consult an endocrinologist or your GYN doc for their recommendation.
Addison's disease is also a rare disease.
Treatment does restore health.
I think it is up to your MD to decide whether to do the tests to make the diagnosis.
TWENTY TWO
SPM
Specialized pro-resolving mediators
If hsCRP greater than one.
Not clear to me why 4 grams of Lovaza is not sufficient?
TWENTY THREE
Methylcobalamin 1mg and methylfolate 0.8-5 mg
PSP 20-50 If homocysteine greater than 6
if B12 less than 500
I think all suspected dementia patients should get B12 levels as per guidelines
In past I did homocysteine levels on all my elderly patient I got away from due to lack of results or the current guidelines at the time.
I have no problem with patients checking their homocysteine.
TWENTY FOUR
ALPHA-LIPOIC ACID 100 MG
N-acetylsteine 500mg
cinnamon one quarter teaspoon
berberine 300-500 mg 3x a time
or
metformin
If fasting insulin greater than 4.5
or fasting glucose greater than 90
or Hemoglobin A1c greater than 5.5
I like Dr. BREDESEN's the criteria above which can be a diagnosis of pre-diabetes which present guidelines do not yet address yet.
I agree with Metformin for a pre-diabetic.
These are tests you should have done.
The four medicines listed before metformin I would not advise.
TWENTY FIVE
ZINC PICOLINATE
ALHA-LIPOIC
N-acetycysteine
PSP
Mn
Vitamin C
IF ZINC LESS THAN 80
or
COPPER/ZINC LESS THAN 1.3
I never did a Zinc level. Seems absurd with American diet.
TWENTY SIX
SAM-E
OR
FOLATE
IF THERE IS DEPRESSION
This may be the most ridiculous recommendation and probably would be grounds for losing his license if the patient committed suicide.
I have treated depression with multiple drugs since 1980 especially PROZAC
TWENTY SEVEN
Huperzine
Take if after 3 months on ReCODE and memory is the primary problem and not on Aricept.
TWENTY EIGHT
CIRS evaluation
Cholestyramine
Intanasal VIP
If evaluation indicates type 3
high C4A
high TGB-beta 1
low MSH
This is incredible.
I would not do this.
TWENTY NINE
Detoxification
xification protocol.
If metals or biotoxins idebtified
This had nothing to do with Alzheimers.
Thirty
Specific antibiotics or antivirals
If infections identified
As an infectious disease specialist I was called to consult of fever of unknown origin.
Alzheimer's is not in the differential of FUO.
Fever and infection can make anyone delirious.
Should not be on an Alzheimers list or long term memory loss.
Thirty one
Discontinue or minimize medications that interfere with cognitive function
This is always a good practice in medicine.
I have done this many times with good results.
However this is not Alzheimers.
It is medication induced.
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